Whatever results the medical researchers have received from their limited research on cannabis with liver disease had been largely contradictory to each other. When the studies were conducted during the early 2000s, researchers suggested a negative influence of cannabis on our liver health.
However, recent studies revealed that cannabis and which also includes CBD can be effectively used for symptom management as well as treatment of various kinds of liver diseases.
How cannabis can interact with our liver
In our human body, the liver is the most important organ that performs more than 500 different functions, that includes:
- Bile production
- Metabolism of alcohol.
- Metabolism of drugs
- Metabolism of medications
- Metabolism of various chemical compounds
Our liver is also one of the vitals in various processes of digestion and is critical for plasma protein production in the blood. Excessive alcohol intake, unhealthy lifestyle factors can contribute to the various degradation of our structure of the liver and their function.
For a better understanding of how cannabis can specifically affect our liver, first, we need to understand how our endocannabinoid system which is also called ECS really works.
Our ECS is a very complex cell-signaling system that is supposed to play a very important role to modulate a different range of functions and processes. All these functions also include our:
- Immune response.
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Naturally, our body can produce endocannabinoids, which can function for regulating various physiological processes that include processes relating to our liver function. Like our endocannabinoids, phytocannabinoids found in various cannabis plants can influence ECS activity.
As per one review, that can affect the receptors CB1 and CB2 of the ECS have fluctuating effects on cirrhosis. Cirrhosis is a disease that is characterized by scarring and damage of our liver.
As the activation of the CB1 receptor will contribute to scarring while activating the CB2 receptor will counteract it. Because CB1 deletion can improve scarring and also fat buildup, while due to the deletion of receptor CB2 will increase inflammation and fat buildup. Please note, all these findings were actually from various studies done on rodents.
Final thoughts on liver disease and cannabis
Plenty of studies were conducted related to liver disease and cannabis and it could demonstrate a few potential benefits that medical cannabis can offer on liver disease both in vitro and also in rodents. The unfortunate fact is the effects of this medical cannabis on our liver disease were found to be conflicting and hence no final conclusion could be drawn.
Cannabis is likely to produce a little different kind of effects based on the certain specific disease states of any individual. Besides that, the medical community also lacks the sufficient amount of appropriate clinical data that are actually needed to arrive at a certain definite conclusion so far as the broad-scale marijuana effects on our liver function are concerned.
If you ever decide to use any medical cannabis for your liver-related problems then you must always consult your doctor first.